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Technology Licensing Opportunities

McMaster University wants you as a commercial partner to collaborate with in order to further develop these technologies.
A Novel Prognostic Factor and Therapeutic Target for Metastatic Prostate Cancer

A Novel Prognostic Factor and Therapeutic Target for Metastatic Prostate Cancer

McMaster researchers have identified a prostate cancer stem cell (PCSC) biomarker that promotes PC metastasis and thus has the potential to be developed as a predictive marker and/or therapeutic target for aggressive PC.

A Novel Prognostic Factor and Therapeutic Target for Metastatic Prostate Cancer - Read More…

An Aqueous Self-Assembly Method to Fabricate Degradable Covalently Cross-Linked Microgels

An Aqueous Self-Assembly Method to Fabricate Degradable Covalently Cross-Linked Microgels

McMaster researchers have developed a method of preparing monodisperse degradable gel-based nanoparticles based on thermoresponsive polymers (e.g. poly(N-isopropylacryalmide), PNIPAM, or poly(oligoethylene glycol methacrylate, POEGMA)) for use in a wide range of medical and other applications.

An Aqueous Self-Assembly Method to Fabricate Degradable Covalently Cross-Linked Microgels - Read More…

Applications of Microvesicles and Exosomes in cancer diagnostics and therapeutics

Applications of Microvesicles and Exosomes in cancer diagnostics and therapeutics

Microvesicles and exosomes are small vesicles released by the cells into their environment. A researcher at McMaster University has discovered that various nuclear receptors can be detected in microvesicles, and transferred from the nucleus of one cell to another using this route of transport. Identified receptors are related to poor prognosis in cancer patients and thus there are implications for this finding in both cancer diagnostics and therapeutics.

Applications of Microvesicles and Exosomes in cancer diagnostics and therapeutics - Read More…

Chlamydia Vaccine

Chlamydia Vaccine

Chlamydias are major disease causing agents of infection affecting over 92 million individuals worldwide. McMaster researchers have evaluated novel Chlamydial proteins as immunogens in animal models for their ability to induce a protective immune response.

Chlamydia Vaccine - Read More…

Detecting and Treating Atherothrombotic Disease

Detecting and Treating Atherothrombotic Disease

McMaster researchers have developed a method for the detection and prevention of atherothrombotic disease. This method is based on the discovery that anti-GRP78 autoantibodies in the bloodstream can accelerate atherosclerotic lesion development and increase the activity of tissue factor, the key cellular initiator of blood coagulation.

Detecting and Treating Atherothrombotic Disease - Read More…

Diagnostic for Endometriosis and other Inflammatory Diseases

Diagnostic for Endometriosis and other Inflammatory Diseases

Non-invasive methods, assays and kits for detecting and monitoring the progress of endometriosis

Diagnostic for Endometriosis and other Inflammatory Diseases - Read More…

Early Rule-Out Biomarker Panel for Cardiovascular Events

Early Rule-Out Biomarker Panel for Cardiovascular Events

A new panel of biomarkers that can be used as an early rule-out test for patients presenting with chest pain in the emergency room.

Early Rule-Out Biomarker Panel for Cardiovascular Events - Read More…

Electro-erosion Edge Honing of Cutting Tools

Electro-erosion Edge Honing of Cutting Tools

This technology employs electro-erosion to create of a hone radius on the edges of cutting tools for conventional metal cutting operations. It is especially beneficial in the edge preparation of cutting tools made from ultra hard materials such as polycrystalline diamond (PCD).

Electro-erosion Edge Honing of Cutting Tools - Read More…

Hydrogel Materials with Improved Wetting Properties for Ophthalmic Use

Hydrogel Materials with Improved Wetting Properties for Ophthalmic Use

These hydrogels contain hyaluronic acid hydrogels making them suitable for for ophthalmic applications . For example, contact lenses made of this material will reduce the end of the day, dry eye problem for the wearer.

Hydrogel Materials with Improved Wetting Properties for Ophthalmic Use - Read More…

Inhibiting Anti-GRP78 Autoantibody Binding

Inhibiting Anti-GRP78 Autoantibody Binding

A potential biomarkers for cancer diagnosis or a therapeutic target for reducing the risk of cancer and its thrombotic complications

Inhibiting Anti-GRP78 Autoantibody Binding - Read More…

Inhibiting lung cancer growth through the Oncostatin M/Oncostatin M receptor axis

Inhibiting lung cancer growth through the Oncostatin M/Oncostatin M receptor axis

By specifically targeting the OSM-OSM receptor pathway, this novel approach allows slowing/stopping tumour growth in the lungs through regulation of activation or recruitment of non-tumour cells and their products.

Inhibiting lung cancer growth through the Oncostatin M/Oncostatin M receptor axis - Read More…

Inhibition of Fatty Acid Synthesis

Inhibition of Fatty Acid Synthesis

McMaster researchers have identified that the combination of salicylate-based drugs, such as Aspirin, with mitochondrial disruptors, can synergistically reduce liver lipid levels and fatty acid synthesis, while improving insulin sensitivity.

Inhibition of Fatty Acid Synthesis - Read More…

Inhibition of Scar Formation in Wound Healing and Internal Organ Fibrosis

Inhibition of Scar Formation in Wound Healing and Internal Organ Fibrosis

This is a novel gene in the process of scar formation in dermal wound healing. A targeted down regulation of this gene by genetic and pharmacological means is expected to prevent scar formation and prevent fibrosis of critical organ systems.

Inhibition of Scar Formation in Wound Healing and Internal Organ Fibrosis - Read More…

Lab-on-a-Chip Target Isolation

Lab-on-a-Chip Target Isolation

Researchers at McMaster University have developed a method for rapid benchtop fabrication of multi-scale micro-electromagnets for capturing magnetic particles on a lab-on-a-chip (LOC) compatible platform.

Lab-on-a-Chip Target Isolation - Read More…

Method for Determining Coagulation Activation in Whole Blood

Method for Determining Coagulation Activation in Whole Blood

Measuring coagulation activation, including thrombin generation, is useful in a number of clinical conditions. McMaster researchers have developed a novel method and class of substrates to do this using whole blood, for instance from a finger prick, using conventional fluorescence equipment.

Method for Determining Coagulation Activation in Whole Blood - Read More…

Method for Measuring Free Thrombin Activity

Method for Measuring Free Thrombin Activity

The invention relates to a new method for monitoring thrombin generation in blood or plasma samples that allows thrombin not bound to A2M to be distinguished from thrombin bound to A2M.

Method for Measuring Free Thrombin Activity - Read More…