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Early Rule-Out Biomarker Panel for Cardiovascular Events
A new panel of biomarkers that can be used as an early rule-out test for patients presenting with chest pain in the emergency room.
Located in Opportunities / Technologies / Technologies Inventory
Novel Approaches in Antibacterial Research
Research into novel antibacterial agents at McMaster University is led by Drs Eric Brown and Gerry Wright, world renowned experts in infectious disease. These researchers have collaborated on several promising approaches to overcome antibiotic resistance and to develop novel anti–infective agents.
Located in Opportunities / / Technologies Inventory / Novel Approaches in Antibacterial Research
Plant-derived Pharmacological Chaperones for Treatment of PKU
Pharmacological chaperones (PCs) are a promising strategy for the treatment of genetic disorders based on enzyme enhancement therapy, such as phenylketonuria (PKU).
Located in Opportunities / Technologies / Technologies Inventory
An Aqueous Self-Assembly Method to Fabricate Degradable Covalently Cross-Linked Microgels
McMaster researchers have developed a method of preparing monodisperse degradable gel-based nanoparticles based on thermoresponsive polymers (e.g. poly(N-isopropylacryalmide), PNIPAM, or poly(oligoethylene glycol methacrylate, POEGMA)) for use in a wide range of medical and other applications.
Located in Opportunities / Technologies / Technologies Inventory
Treatment of Breast Cancer
THRα1 Inhibition | THRα2 Up-regulation | Induction of Hypothyroidism
Located in Opportunities / Technologies / Technologies Inventory
Novel Antistaphylococcal Combination Therapy
McMaster researchers have now discovered a non-antibiotic, previously approved compound that greatly potentiates the antibacterial activity of the broad spectrum beta-lactam antibiotics.
Located in Opportunities / Technologies / Technologies Inventory
Novel Antibacterial Inhibitors that target Biosynthetic Pathways
Professor Eric Brown has developed a novel screening approach for antibacterial inhibitors.
Located in Opportunities / Technologies / Technologies Inventory
Method to Target Ultrasound Contrast Agents to Sites of Disease
McMaster Researchers have discovered a new approach to ultrasound molecular imaging that employs covalent and highly selective capture of functionalized MB’s in vivo using a pretargeting strategy.
Located in Opportunities / Technologies / Technologies Inventory
Inhibiting lung cancer growth through the Oncostatin M/Oncostatin M receptor axis
By specifically targeting the OSM-OSM receptor pathway, this novel approach allows slowing/stopping tumour growth in the lungs through regulation of activation or recruitment of non-tumour cells and their products.
Located in Opportunities / Technologies / Technologies Inventory
File Hydrogel Materials with Improved Wetting Properties for Ophthalmic Use
These hydrogels contain hyaluronic acid hydrogels making them suitable for for ophthalmic applications . For example, contact lenses made of this material will reduce the end of the day, dry eye problem for the wearer.
Located in Opportunities / / Technologies Inventory / Hydrogel Materials with Improved Wetting Properties for Ophthalmic Use