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Identifying Mechanism of Action for Novel Drugs using a Transcriptional Response Database and Deep Learning
Custom 3D printed hardware and a deep learning predictive model for creating transcriptional fingerprints of bioactive molecules in bacteria.
Located in Opportunities / / Technologies Inventory / Identifying Mechanism of Action for Novel Drugs using a Transcriptional Response Database and Deep Learning
Identifying Mechanism of Action for Novel Drugs using a Transcriptional Response Database and Deep Learning
Custom 3D printed hardware and a deep learning predictive model for creating transcriptional fingerprints of bioactive molecules in bacteria
Located in Opportunities / Technologies / Technologies Inventory
Plant-Derived Pharmacological Chaperones for Treatment of Phenylketonuria (PKU)
These plant-derived natural products offer a safe, yet effective, therapeutic treatment of PKU via nutritional supplementation.
Located in Opportunities / Technologies / Technologies Inventory
An Aqueous Self-Assembly Method to Fabricate Degradable Covalently Cross-Linked Microgels
McMaster researchers have developed a method of preparing monodisperse degradable gel-based nanoparticles based on thermoresponsive polymers (e.g. poly(N-isopropylacryalmide), PNIPAM, or poly(oligoethylene glycol methacrylate, POEGMA)) for use in a wide range of medical and other applications.
Located in Opportunities / Technologies / Technologies Inventory
Dronedarone Breast Cancer Therapy
Dronedarone is an FDA-approved drug that has shown anti-cancer activity in breast cancer cell cultures, sphere forming assays and in mice.
Located in Opportunities / Technologies / Technologies Inventory
Antibiotic Resistance Platform (ARP) for Adjuvant Discovery and Antibiotic Dereplication
The platform consists of a cell-based library of Escherichia coli expressing individual resistance genes
Located in Opportunities / Technologies / Technologies Inventory
Comprehensive Antibiotic Resistance Database (CARD)
A bioinformatics resource for antimicrobial resistance (AMR) surveillance in healthcare, agriculture and environmental settings.
Located in Opportunities / Technologies / Technologies Inventory
Method to Target Ultrasound Contrast Agents to Sites of Disease
McMaster Researchers have discovered a new approach to ultrasound molecular imaging that employs covalent and highly selective capture of functionalized MB’s in vivo using a pretargeting strategy.
Located in Opportunities / Technologies / Technologies Inventory
File Hydrogel Materials with Improved Wetting Properties for Ophthalmic Use
These hydrogels contain hyaluronic acid hydrogels making them suitable for for ophthalmic applications . For example, contact lenses made of this material will reduce the end of the day, dry eye problem for the wearer.
Located in Opportunities / / Technologies Inventory / Hydrogel Materials with Improved Wetting Properties for Ophthalmic Use
File Laboratory Scores for Risk Stratification of Patients with Possible Cardiac Injury
Using important biochemical parameters to accurately determine the risk of an acute cardiovascular event or death with easy interpretation.
Located in Opportunities / / Technologies Inventory / New Tools to Fight Thrombotic Disease